SPIB
Sign in to saveAlso known as SPI-B, Spi-B transcription factor
Transcription factor Spi-B is a protein that in humans is encoded by the SPIB gene.
In the Vinony graph
Within Vinony's link graph, SPIB is referenced by 815 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 19 and Transcription factors.
Its subject is documented across 6 Wikipedia language editions.
Gene data
SPIB- Name
- Spi-B transcription factor
- Type
- protein-coding
- Position
- 50,418,931–50,431,314 (+)
- Aliases
- SPI-B
- Ensembl
- ENSG00000269404
- RefSeq RNA
- NM_001243998.2, NM_001243999.2, NM_001244000.2, NM_003121.5
- RefSeq protein
- NP_001230927.1, NP_001230928.1, NP_001230929.2, NP_003112.2
The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
Spi-B transcription factor
- Symbol
- SPIB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:50,418,931-50,431,314
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 79220
- genetic association
- primary biliary cholangitis
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6689
- genomic start
- 50922195
- chromosome
- human chromosome 19
- genomic end
- 50431314
- cytogenetic location
- 19q13.33
- expressed in
- blood
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Transcription factor Spi-B is a protein that in humans is encoded by the SPIB gene.
== Function ==
Excerpted from Wikipedia’s “SPIB” article, available under the CC BY-SA 4.0 licence.