STK10
Sign in to saveAlso known as LOK, PRO2729, serine/threonine kinase 10
Serine/threonine-protein kinase 10 is an enzyme that in humans is encoded by the STK10 gene.
In the Vinony graph
Within Vinony's link graph, STK10 is referenced by 300 other articles, and connects out to protein-serine-threonine kinases, PubMed and human chromosome 5.
It sits within the topics EC 2.7.11 and Genes on human chromosome 5.
Its subject is documented across 6 Wikipedia language editions.
Gene data
STK10- Name
- serine/threonine kinase 10
- Type
- protein-coding
- Aliases
- LOK, PRO2729
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
serine/threonine kinase 10
- Symbol
- STK10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:172,042,079-172,188,411
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PBB Protein STK10 image.jpg
Show 8 more facts
- HomoloGene ID
- 38122
- genomic start
- 172042079
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6793
- genomic end
- 172188224
- chromosome
- human chromosome 5
- cytogenetic location
- 5q35.1
- expressed in
- lymph node
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Serine/threonine-protein kinase 10 is an enzyme that in humans is encoded by the STK10 gene.
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
Excerpted from Wikipedia’s “STK10” article, available under the CC BY-SA 4.0 licence.