STK10
Sign in to saveAlso known as LOK, PRO2729, serine/threonine kinase 10
Serine/threonine-protein kinase 10 is an enzyme that in humans is encoded by the STK10 gene.
Gene data
STK10- Name
- serine/threonine kinase 10
- Type
- protein-coding
- Aliases
- LOK, PRO2729
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- PBB Protein STK10 image.jpg
Show 5 more facts
- HomoloGene ID
- 38122
- genomic start
- 172042079
- exact match
- identifiers.org/ncbigene/6793
- genomic end
- 172188224
- cytogenetic location
- 5q35.1
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- Further reading
Serine/threonine-protein kinase 10 is an enzyme that in humans is encoded by the STK10 gene.
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.