Structure via PubChem · Public domain (PubChem)
talastine
Sign in to saveTalastine (trade name Ahanon) is an antihistamine.
Chemical data
- Formula
- C19H21N3O
- Molecular weight
- 307.4 g/mol
- IUPAC name
- 4-benzyl-2-[2-(dimethylamino)ethyl]phthalazin-1-one
- SMILES
- CN(C)CCN1C(=O)C2=CC=CC=C2C(=N1)CC3=CC=CC=C3
- InChIKey
- LCAAMXMULMCKLJ-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 35.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- allergic disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 307.168
Show 2 more facts
- canonical SMILES
- CN(C)CCN1C(=O)C2=CC=CC=C2C(=N1)CC3=CC=CC=C3
- chemical formula
- C₁₉H₂₁N₃O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- References
- External links
Talastine (trade name Ahanon) is an antihistamine.
==Synthesis== The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with dimethylaminoethyl chloride.
Excerpted from Wikipedia’s “talastine” article, available under the CC BY-SA 4.0 licence.