Tubuline
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. It was discovered and named by Hideo Mōri in 1968. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division.
Key facts
- Protein family.Symbol
- Tubulin
- Protein family.Name
- Tubulin
- Protein family.image
- PDB 1ia0 EBI.jpg
- Protein family.caption
- kif1a head-microtubule complex structure in atp-form
- Protein family.Pfam
- PF00091
- Protein family.Pfam_clan
- CL0442
- Protein family.InterPro
- IPR003008
- Protein family.PROSITE
- PDOC00201
- Protein family.SCOP
- 1tub
via Wikipedia infobox
Wikidata facts
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- Commons category
- Tubulin
Article · Français
La tubuline est la protéine structurale des microtubules, un constituant majeur du cytosquelette. Elle a une masse moléculaire d'environ 100 kDa.
Abstract from DBpedia / Wikipedia · CC BY-SA