Category
page 2Genes on human chromosome 19
ADGRE2
EGF-like module-containing mucin-like hormone receptor-like 2 also known as CD312 (cluster of differentiation 312) is a protein encoded by the ADGRE2 gene. EMR2 is a member of the adhesion GPCR family.
Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
smooth muscle protein/calponin
Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase, which is dependent upon calcium binding to calmodulin, releases the calponin's inhibition of the smooth muscle ATPase.
RAB3A
Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. It is involved in calcium-triggered exocytosis in neurons.
ZNF224
Zinc finger protein 224 is a protein that in humans is encoded by the ZNF224 gene.
glycogen synthase
enzyme class, includes alll types of glycogen/starch synthases
CYTH2
Cytohesin-2 is a protein that in humans is encoded by the CYTH2 gene.
RRAS
Ras-related protein R-Ras is a protein that in humans is encoded by the RRAS gene.
SIRT6
protein-coding gene in the species Homo sapiens
HMG20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related is a protein that in humans is encoded by the HMG20B gene.
CEACAM1 protein
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family.
complement factor D
class of enzymes
CD209
DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209 (Cluster of Differentiation 209) is a protein which in humans is encoded by the CD209 gene.
CLEC4M
C-type lectin domain family 4 member M is a protein that in humans is encoded by the CLEC4M gene. CLEC4M has also been designated as CD299 (cluster of differentiation 299).
Solute carrier family 5 member 5
mammalian protein found in Homo sapiens
ERCC excision repair 2, TFIIH core complex helicase subunit
TFIIH subunit XPD is a protein that in humans is encoded by the ERCC2 (ERCC excision repair 2) gene. It is a component of the general transcription and DNA repair factor IIH (TFIIH) core complex involved in transcription-coupled nucleotide excision repair.
KEAP1
Kelch-like ECH-associated protein 1 is an E3 ubiquitin ligase that in humans is encoded by the Keap1 gene.
MADCAM1
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a protein that in humans is encoded by the MADCAM1 gene. The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4 / beta7), L-selectin, and VLA-4 (alpha4 / beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.
Plasminogen activator, urokinase receptor
mammalian protein found in Homo sapiens
PDCD5
Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene.
TYK2
protein-coding gene in the species Homo sapiens
NLRP7
NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene.
HAS1
Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene.
P2RY11
P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.
RGS9BP
Regulator of G protein signaling 9 binding protein is a protein that in humans is encoded by the RGS9BP gene.
GDF15
Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as Macrophage inhibitory cytokine-1 (MIC-1).
CEA cell adhesion molecule 8
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (Cluster of Differentiation 66b), is a member of the carcinoembryonic antigen (CEA) gene family. Its main function is cell adhesion, cell migration, and pathogen binding.
DNMT1
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) is an enzyme that catalyzes the transfer of methyl groups to specific CpG sites in DNA, a process called DNA methylation. In humans, it is encoded by the DNMT1 gene. Dnmt1 forms part of the family of DNA methyltransferase enzymes, which consists primarily of DNMT1, DNMT3A, and DNMT3B.
ADGRE1
EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene.
CD79a molecule
Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.
MEX3D
Mex-3 homolog D (C. elegans), also known as MEX3D, is a protein that in humans is encoded by the MEX3D gene.
uroplakin 1A
Uroplakin-1a (UP1a) is a protein that in humans is encoded by the UPK1A gene.
Fc fragment of IgA receptor
Fc fragment of IgA receptor (FCAR) is a human gene that codes for the transmembrane receptor FcαRI, also known as CD89 (Cluster of Differentiation 89). FcαRI binds the heavy-chain constant region of Immunoglobulin A (IgA) antibodies. FcαRI is present on the cell surface of myeloid lineage cells, including neutrophils, monocytes, macrophages, and eosinophils, though it is notably absent from intestinal macrophages and does not appear on mast cells. FcαRI plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. Inside-out signaling primes FcαRI in order for
C5AR2
Complement component 5a receptor 2 is a protein of the complement system that in humans is encoded by the C5AR2 gene. It is highly expressed in the blood and spleen, predominantly by myeloid cells.
NLRP4
NACHT, LRR and PYD domains-containing protein 4 is a protein that in humans is encoded by the NLRP4 gene.
DHPS
Deoxyhypusine synthase is an enzyme that in humans is encoded by the DHPS gene.
ATP1A3
Sodium/potassium-transporting ATPase subunit alpha-3 is an enzyme that in humans is encoded by the ATP1A3 gene.
FSTL3
Follistatin-related protein 3 (also known as follistatin-like protein 3) is a protein that in humans is encoded by the FSTL3 gene.
ARHGAP35
Glucocorticoid receptor DNA-binding factor 1 is a protein that in humans is encoded by the GRLF1 gene.
ZNF274
Zinc finger protein 274 is a protein that in humans is encoded by the ZNF274 gene.
GP6
protein-coding gene in the species Homo sapiens
AP2S1
AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.
GNA11
Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.
CDKN2D
Cyclin-dependent kinase 4 inhibitor D is an enzyme that in humans is encoded by the CDKN2D gene.
CCNE1
protein-coding gene in the species Homo sapiens
KLK14
Kallikrein-14 is a protein that in humans is encoded by the KLK14 gene.
ARID3A
AT-rich interactive domain-containing protein 3A is a protein that in humans is encoded by the ARID3A gene.
ZNF83
Zinc finger protein 83 is a protein that in humans is encoded by the ZNF83 gene.
CEBPG
CCAAT/enhancer-binding protein gamma (C/EBPγ) is a protein that in humans is encoded by the CEBPG gene. This gene has no introns.
LYPD3
Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene.
ATF5
Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ATF5 gene.
CYP2A13
Cytochrome P450 2A13 is a protein that in humans is encoded by the CYP2A13 gene.
CD70 molecule
CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. CD70 is also known as a ligand for CD27.
alpha-mannosidase
thumb|Cartoon depiction of the protein Streptococcus pyogenes family GH38 α-Mannosidase created using PyMol.
KLK5
Kallikrein-5, formerly known as stratum corneum tryptic enzyme (SCTE), is a serine protease expressed in the epidermis. In humans it is encoded by the KLK5 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. Alternative splicing results in multiple transcript variants encoding the same protein.
SUGP2
Putative splicing factor, arginine/serine-rich 14 is a protein that in humans is encoded by the SFRS14 gene.
NLRP2
NACHT, LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene.
KLK1
Kallikrein-1 is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family.
RAD23A
UV excision repair protein RAD23 homolog A is a protein that in humans is encoded by the RAD23A gene.
GAPDHS
Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic or glyceraldehyde-3-phosphate dehydrogenase, testis-specific is an enzyme that in humans is encoded by the GAPDHS gene.
IRF3
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor.