Proteins

26S proteasome non-ATPase regulatory subunit 10 or gankyrin is an enzyme that in humans is encoded by the PSMD10 gene. First isolated in 1998 by Tanaka et al.; Gankyrin is an oncoprotein that is a component of the 19S regulatory cap of the proteasome. Structurally, it contains a 33-amino acid ankyrin repeat that forms a series of alpha helices. It plays a key role in regulating the cell cycle via protein-protein interactions with the cyclin-dependent kinase CDK4. It also binds closely to the E3 ubiquitin ligase MDM2, which is a regulator of the degradation of p53 and retinoblastoma protein, bo

transcription factor

protein-coding gene in the species Homo sapiens

transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH

extract from hemp

Methemalbumin (MHA) is an albumin complex consisting of albumin and heme.

T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene. This gene is also known by several other names: T-Brain 1, TBR-1, TES-56, and MGC141978. TBR1 is a member of the TBR1 subfamily of T-box family transcription factors, which share a common DNA-binding domain. Other members of the TBR1 subfamily include EOMES and TBX21. TBR1 is involved in the differentiation and migration of neurons and is required for normal brain development. TBR1 interacts with various genes and proteins in order to regulate cortical development, spec

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Caldesmon is a protein that in humans is encoded by the CALD1 gene.

InterPro Family

mammalian protein found in Homo sapiens

class of enzymes

Left-right determination factor 2 (Lefty2) aka TGFB4 is a protein that is encoded by the LEFTY2 gene in humans.

protein-coding gene in the species Homo sapiens

GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene.

mammalian protein found in Homo sapiens

Septins are a group of GTP-binding proteins expressed in all eukaryotic cells except plants. Different septins form protein complexes with each other. These complexes can further assemble into filaments, rings and gauzes. Assembled as such, septins function in cells by localizing other proteins, either by providing a scaffold to which proteins can attach, or by forming a barrier preventing the diffusion of molecules from one compartment of the cell to another, or in the cell cortex as a barrier to the diffusion of membrane-bound proteins.

Immunoglobulin kappa locus, also known as IGK@, is a region on the p arm of human chromosome 2, region 11.2 (2p11.2), that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).

protein-coding gene in the species Homo sapiens

InterPro Family

AP-1 complex subunit gamma-1 is a protein that in humans is encoded by the AP1G1 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene. The human BARD1 protein is 777 amino acids long and contains a RING finger domain (residues 46-90), four ankyrin repeats (residues 420-555), and a tandem BRCT domain (residues 568-777).

protein-coding gene in the species Homo sapiens

InterPro Family

Pleckstrins are a family of proteins found in platelets and other cells. The name derives from platelet and leukocyte C kinase substrate and the KSTR string of amino acids. The prototype protein, now called pleckstrin-1, was first identified in 1979 as the major substrate of protein kinase C in platelets. The homolog pleckstrin-2 is more widely expressed in tissues.

Zinc finger protein 202 is a transcription factor first associated with breast cancer. It is a protein that, in humans, is encoded by the ZNF202 gene.

protein-coding gene in the species Homo sapiens

type of enzymes

Nicastrin, also known as NCSTN, is a protein that in humans is encoded by the NCSTN gene.

Trichosanthin is a ribosome-inactivating protein. It is derived from Trichosanthes kirilowii. It is also an abortifacient.

Acyl-CoA thioesterase 13 is a protein that in humans is encoded by the ACOT13 gene. This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation.

protein family

The endosomal sorting complexes required for transport (ESCRT) proteins are part of a pathway inside cells that helps sort and move other proteins. One of their main jobs is to form structures called multivesicular bodies (MVBs) which help sending of certain proteins, especially ones tagged for removal, to compartments in the cell called lysosomes where they get broken down.

protein-coding gene in the species Homo sapiens

protein with 4 quaternary-structure-subunits

thumb|Biological assembly of SHOC2 protein as shown by crystal structure to a resolution of 2.4 Angstrom. Sulfate molecules are labeled purple. Structure from 10.2210/pdb7TVG/pdb.thumb|SHOC2 protein leucine rich domain. Leucine amino acids shown as bright orange sticks.Leucine-rich repeat (LRR) protein SHOC-2 is a protein that in humans is encoded by the SHOC2 gene. The best-studied role of SHOC2 is in modulating signals of the extracellular signal-regulated kinase 1 and 2 (ERK1/2) pathway by forming a holophosphatase complex that activates RAF proteins. This protein was initially identified i

method used for evaluating the quality of protein in food

protein family

Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), tazarotene-induced gene 2 protein (TIG2), or RAR-responsive protein TIG2 is a protein that in humans is encoded by the RARRES2 gene.

Ankyrin repeat and zinc finger domain-containing protein 1 is a protein that in humans is encoded by the ANKZF1 gene.

Acyl-CoA dehydrogenase family, member 10 is a protein that in humans is encoded by the ACAD10 gene.

Κ-casein, or kappa casein, is a mammalian milk protein involved in several important physiological processes. Chymosin (found in rennet) splits K-casein into an insoluble peptide (para kappa-casein) and water-soluble glycomacropeptide (GMP). GMP is responsible for an increased efficiency of digestion, prevention of neonate hypersensitivity to ingested proteins, and inhibition of gastric pathogens. The human gene for κ-casein is CSN3.

concentrated form of the proteins found in the leaves of plants

protein-coding gene in the species Homo sapiens

method used to determine if a protein is complete

Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP), is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post-synaptic density.

Claudin-17 is a protein that in humans is encoded by the CLDN17 gene. It belongs to the group of claudins; claudins are cell-cell junction proteins that keep that maintains cell- and tissue-barrier function. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.

protein-coding gene in the species Homo sapiens

Nebulette is a cardiac-specific isoform belonging to the nebulin family of proteins. It is encoded by the NEBL gene. This family is composed of 5 members: nebulette, nebulin, N-RAP, LASP-1 and LASP-2. Nebulette localizes to Z-discs of cardiac muscle and appears to regulate the length of actin thin filaments.

protein-coding gene in the species Homo sapiens

C2orf16 is a protein that in humans is encoded by the C2orf16 gene. Isoform 2 of this protein (NCBI ID: CAH18189.1 henceforth referred to as C2orf16) is 1,984 amino acids long. The gene contains 1 exon and is located at 2p23.3. Aliases for C2orf16 include Open Reading Frame 16 on Chromosome 2 and P-S-E-R-S-H-H-S Repeats Containing Sequence.

Protein fold class, typically <100 amino acids long

Invasins are a class of bacterial proteins associated with the penetration of pathogens into host cells. Invasins play a role in promoting entry during the initial stage of infection.

Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 also known as TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene.

TIMELESS-interacting protein (TIPIN) is a protein that in humans is encoded by the TIPIN gene.

Coiled-coil domain-containing protein 138, also known as CCDC138, is a human protein encoded by the CCDC138 gene. The exact function of CCDC138 is unknown.

inclusion bodies for misfolded proteins