Amodiaquine
Also known as Flavoquine, Camoquin, GNF-Pf-5648, Amodiaquinum, Amodiaquina, SJ000110703
Amodiaquine (ADQ) is a medication used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. It is recommended to be given with artesunate to reduce the risk of resistance. Due to the risk of rare but serious side effects, it is not generally recommended to prevent malaria. Though, the World Health Organization (WHO) in 2013 recommended use for seasonal preventive in children at high risk in combination with sulfadoxine and pyrimethamine.
Chemical data
- Formula
- C20H22ClN3O
- Molecular weight
- 355.9 g/mol
- IUPAC name
- 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylazaniumyl)methyl]phenolate
- SMILES
- CC[NH+](CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)[O-]
- InChIKey
- OVCDSSHSILBFBN-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 52.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem