Structure via PubChem · Public domain (PubChem)
delucemine
Sign in to saveAlso known as 3,3-bis(3-fluorophenyl)-N-methylpropan-1-amine
Delucemine (NPS-1506) is a drug which acts as an NMDA antagonist and a serotonin reuptake inhibitor, and has neuroprotective effects. It was originally investigated for the treatment of stroke and in 2004 was studied as a potential antidepressant.
In the Vinony graph
Vinony's link graph records 705 inbound references to delucemine, and connects out to histamine antagonist, dextropropoxyphene and pentamidine.
Vinony files it under 3-Fluorophenyl compounds, Abandoned drugs and Chemical pages without DrugBank identifier.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C16H17F2N
- Molecular weight
- 261.31 g/mol
- IUPAC name
- 3,3-bis(3-fluorophenyl)-N-methylpropan-1-amine
- SMILES
- CNCCC(C1=CC(=CC=C1)F)C2=CC(=CC=C2)F
- InChIKey
- MUGNLPWYHGOJEG-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 12 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 261.133
Show 3 more facts
- chemical formula
- C₁₆H₁₇F₂N
- canonical SMILES
- CNCCC(C1=CC(=CC=C1)F)C2=CC(=CC=C2)F
- Commons category
- Delucemine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Origin
- See also
- References
Delucemine (NPS-1506) is a drug which acts as an NMDA antagonist and a serotonin reuptake inhibitor, and has neuroprotective effects. It was originally investigated for the treatment of stroke and in 2004 was studied as a potential antidepressant.
== Origin == The structure of delucemine is based on argiotoxin 636, a NMDA antagonist isolated from the venom of Argiope aurantia.
Excerpted from Wikipedia’s “delucemine” article, available under the CC BY-SA 4.0 licence.