EntityQ553223· pop 34· linked from 187 articles

esomeprazole

Esomeprazole, sold under the brand name Nexium (or Neksium) among others, is a medication which reduces stomach acid. It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. Its effectiveness is similar to that of other proton pump inhibitors (PPIs). It is taken by mouth or injection into a vein.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 477167063
Drug.image: Esomeprazole.svg
Drug.image_class: skin-invert-image
Drug.width: 245
Drug.image2: Esomeprazole ball-and-stick model.png
Drug.image_class2: bg-transparent
Drug.width2: 250
Drug.tradename: Nexium, others
Drug.MedlinePlus: a699054
Drug.DailyMedID: Esomeprazole
Drug.pregnancy_AU: B3
Drug.routes_of_administration: By mouth, intravenous
Drug.class: Proton pump inhibitor
Drug.ATC_prefix: A02
Drug.ATC_suffix: BC05
Drug.legal_AU: S2

via Wikipedia infobox

Article

18 sections

Contents

Medical use
Gastroesophageal reflux disease
Duodenal ulcers
Efficacy
Adverse effects
Interactions
Pharmacokinetics
Dosage forms
Multiple-unit pellet system
Society and culture
Global distribution
Economics
Controversy
Brand names
Veterinary use
Other uses
References
Further reading

Common side effects include headache, constipation, dry mouth, and abdominal pain. Serious side effects may include angioedema, Clostridioides difficile infection, and pneumonia. Use in pregnancy appears to be safe, while safety during breastfeeding is unclear. Esomeprazole is the (S)-(−)-enantiomer (or less specifically the S-isomer) of omeprazole. It works by blocking H+/K+-ATPase in the parietal cells of the stomach.