gepirone
Sign in to saveGepirone, sold under the brand name Exxua, is a medication used for the treatment of major depressive disorder. It is taken orally.
Key facts
- Drug.O
- 2
- Drug.tradename
- Exxua
- Drug.width2
- 260
- Drug.N
- 5
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 437181944
- Drug.image
- Gepirone.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.image2
- Gepirone_3D_ball-and-stick.png
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- N06
- Drug.ATC_suffix
- AX19
- Drug.legal_US
- Rx-only
- Drug.bioavailability
- 14–17%
- Drug.protein_bound
- 72%
- Drug.metabolism
- CYP3A4
- Drug.metabolites
- 3'-OH-gepirone; 1-(2-Pyrimidinyl)piperazine
via Wikipedia infobox
Chemical data
- Formula
- C19H29N5O2
- Molecular weight
- 359.5 g/mol
- IUPAC name
- 4,4-dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione
via PubChem
Article
20 sectionsContents
- Medical uses
- Available forms
- Specific populations
- Contraindications
- Side effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Chemistry
- History
- Society and culture
- Names
- Research
- See also
- References
Gepirone, sold under the brand name Exxua, is a medication used for the treatment of major depressive disorder. It is taken orally.
Side effects of gepirone include dizziness, nausea, insomnia, abdominal pain, and dyspepsia (indigestion). Gepirone acts as a partial agonist of the serotonin 5-HT1A receptor. An active metabolite of gepirone, 1-(2-pyrimidinyl)piperazine, is an α2-adrenergic receptor antagonist. Gepirone is a member of the azapirone group of compounds.