HMGN3
Sign in to saveAlso known as PNAS-25, TRIP7, PNAS-24, high mobility group nucleosomal binding domain 3
High mobility group nucleosome-binding domain-containing protein 3 is a protein that in humans is encoded by the HMGN3 gene.
In the Vinony graph
Within Vinony's link graph, HMGN3 is referenced by 813 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Its subject is documented across 6 Wikipedia language editions.
Gene data
HMGN3- Name
- high mobility group nucleosomal binding domain 3
- Type
- protein-coding
- Aliases
- PNAS-24, PNAS-25, TRIP7
The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016].
via MyGene.info
Gene · Ensembl
high mobility group nucleosomal binding domain 3
- Symbol
- HMGN3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:79,199,425-79,234,862
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 130417
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9324
- genomic end
- 79944406
- genomic start
- 79910962
- chromosome
- human chromosome 6
- cytogenetic location
- 6q14.1
- Commons category
- HMGN3
- expressed in
- germinal epithelium
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
High mobility group nucleosome-binding domain-containing protein 3 is a protein that in humans is encoded by the HMGN3 gene.
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “HMGN3” article, available under the CC BY-SA 4.0 licence.