ICAM2

Also known as CD102, intercellular adhesion molecule 2

Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a human gene, and the protein resulting from it.

In the Vinony graph

Vinony's link graph records 368 inbound references to ICAM2, and connects out to PubMed, Ensembl genome database project and CD1.

It is catalogued under topics including Clusters of differentiation and Genes on human chromosome 17.

Vinony links it to 8 Wikipedia language editions.

Gene data

ICAM2

Name: intercellular adhesion molecule 2
Type: protein-coding
Position: 64,002,594–64,020,640 (−)
Aliases: CD102
Ensembl: ENSG00000108622
RefSeq RNA: NM_000873.4, NM_001099786.2, NM_001099787.2, NM_001099788.2, NM_001099789.2
RefSeq protein: NP_000864.2, NP_001093256.1, NP_001093257.1, NP_001093258.1, NP_001093259.1

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways

Cell adhesion molecules - Homo sapiens (human)Natural killer cell mediated cytotoxicity - Homo sapiens (human)Adaptive Immune System Adaptive Immune System Extracellular matrix organization Innate Immune System Immune System Immune System Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions

via MyGene.info

Gene · Ensembl

intercellular adhesion molecule 2

Symbol: ICAM2
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:64,002,594-64,020,640
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein ICAM2 PDB 1zxq.png

Show 7 more facts

HomoloGene ID: 675
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/3384
genomic end: 62097994
genomic start: 62079954
chromosome: human chromosome 17
cytogenetic location: 17q23.3

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

7 sections

Contents

Protein structure
Protein functions
Interactions
See also
References
Further reading
External links

Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a human gene, and the protein resulting from it.

==Protein structure== The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2–9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein.

Excerpted from Wikipedia’s “ICAM2” article, available under the CC BY-SA 4.0 licence.