IRAK2
Sign in to saveAlso known as IRAK-2, interleukin 1 receptor associated kinase 2
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene.
In the Vinony graph
Within Vinony's link graph, IRAK2 is referenced by 115 other articles, and connects out to PubMed, human chromosome 3 and interferon gamma.
It sits within the topics EC 2.7.11 and Genes on human chromosome 3.
Its subject is documented across 4 Wikipedia language editions.
Gene data
IRAK2- Name
- interleukin 1 receptor associated kinase 2
- Type
- protein-coding
- Position
- 10,164,862–10,243,756 (+)
- Aliases
- IRAK-2
- Ensembl
- ENSG00000134070
- RefSeq RNA
- NM_001570.4
- RefSeq protein
- NP_001561.3
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interleukin 1 receptor associated kinase 2
- Symbol
- IRAK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:10,164,862-10,243,756
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 1207
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3656
- genomic end
- 10243745
- genomic start
- 10164919
- expressed in
- islet of Langerhans
- chromosome
- human chromosome 3
- cytogenetic location
- 3p25.3
- Commons category
- IRAK2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene.
== Function ==
Excerpted from Wikipedia’s “IRAK2” article, available under the CC BY-SA 4.0 licence.