KLK2
Sign in to saveAlso known as KLK2A2, hGK-1, hK2, kallikrein related peptidase 2
Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue.
In the Vinony graph
Vinony's link graph records 139 inbound references to KLK2, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 5 Wikipedia language editions.
Gene data
KLK2- Name
- kallikrein related peptidase 2
- Type
- protein-coding
- Position
- 50,861,568–50,880,567 (+)
- Aliases
- KLK2A2, hGK-1, hK2
- Ensembl
- ENSG00000167751
- RefSeq RNA
- NM_001002231.3, NM_001002232.2, NM_001256080.2, NM_005551.5, NR_045762.2
- RefSeq protein
- NP_001002231.1, NP_001243009.1, NP_005542.1
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
kallikrein related peptidase 2
- Symbol
- KLK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:50,861,568-50,880,567
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 124422
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3817
- genomic end
- 51383823
- genomic start
- 51364824
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.33
- expressed in
- urethra
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue.
== References ==
Excerpted from Wikipedia’s “KLK2” article, available under the CC BY-SA 4.0 licence.