LHX6
Sign in to saveAlso known as LHX6.1, LIM homeobox 6, hLHX6
LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.
In the Vinony graph
Within Vinony's link graph, LHX6 is referenced by 3 other articles, and connects out to PubMed, human chromosome 9 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 9 and Transcription factors.
Its subject is documented across 6 Wikipedia language editions.
Gene data
LHX6- Name
- LIM homeobox 6
- Type
- protein-coding
- Position
- 122,202,577–122,229,626 (−)
- Aliases
- LHX6.1, hLHX6
- Ensembl
- ENSG00000106852
- RefSeq RNA
- NM_001242333.2, NM_001242334.2, NM_001242335.2, NM_001348190.2, NM_014368.5
- RefSeq protein
- NP_001229262.1, NP_001229263.1, NP_001229264.1, NP_001335119.1, NP_055183.2
This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein has tandem LIM domains as well as a DNA-binding homeodomain. The protein functions as a transcription factor involved in embryogenesis and head development and is highly expressed in neural crest derived mesenchyme cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
LIM homeobox 6
- Symbol
- LHX6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:122,202,577-122,229,626
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7401
- exact match
- identifiers.org/ncbigene/26468
- found in taxon
- Homo sapiens
- genomic end
- 124991905
- genomic start
- 124964856
- chromosome
- human chromosome 9
- cytogenetic location
- 9q33.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.
This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Excerpted from Wikipedia’s “LHX6” article, available under the CC BY-SA 4.0 licence.