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Ro48-8684
Sign in to saveRo48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s, which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice.
In the Vinony graph
Vinony's link graph records 539 inbound references to Ro48-8684, and connects out to benzodiazepine drug, alphenal and zapizolam.
Vinony files it under Abandoned drugs, Chemical pages without DrugBank identifier and Drugboxes which contain changes to watched fields.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C22H26FN5O2
- Molecular weight
- 411.5 g/mol
- IUPAC name
- 3-[5-[(dipropylamino)methyl]-1,3-oxazol-2-yl]-8-fluoro-5-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
- SMILES
- CCCN(CCC)CC1=CN=C(O1)C2=C3CN(C(=O)C4=C(N3C=N2)C=CC(=C4)F)C
- InChIKey
- YKKLHEHNUYCLQQ-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 67.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 411.207053
Show 2 more facts
- chemical formula
- C₂₂H₂₆FN₅O₂
- canonical SMILES
- CCCN(CCC)CC1=CN=C(O1)C2=C3CN(C(=O)C4=C(N3C=N2)C=CC(=C4)F)C
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Ro48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s, which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice.
== See also == Benzodiazepine
Excerpted from Wikipedia’s “Ro48-8684” article, available under the CC BY-SA 4.0 licence.