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Structure via PubChem · Public domain (PubChem)
FG-8205
Sign in to saveFG-8205 (L-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at GABAA receptors, with slight selectivity for the α1-containing subtype. In animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced.
In the Vinony graph
Vinony's link graph records 539 inbound references to FG-8205, and connects out to benzodiazepine drug, alphenal and zapizolam.
It is catalogued under topics including Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields and Drugboxes which contain changes to watched fields.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C17H16ClN5O2
- Molecular weight
- 357.8 g/mol
- IUPAC name
- 7-chloro-5-methyl-3-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
- SMILES
- CC(C)C1=NC(=NO1)C2=C3CN(C(=O)C4=C(N3C=N2)C=CC=C4Cl)C
- InChIKey
- SEWXZWMBVGJJPG-UHFFFAOYSA-N
- XLogP
- 2.4
- Polar surface area
- 77.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 357.099
Show 2 more facts
- chemical formula
- C₁₇H₁₆ClN₅O₂
- canonical SMILES
- CC(C)C1=NC(=NO1)C2=C3CN(C(=O)C4=C(N3C=N2)C=CC=C4Cl)C
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
FG-8205 (L-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at GABAA receptors, with slight selectivity for the α1-containing subtype. In animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced.
==See also== Benzodiazepine
Excerpted from Wikipedia’s “FG-8205” article, available under the CC BY-SA 4.0 licence.