SAE1
Sign in to saveAlso known as AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1
SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.
Gene data
SAE1- Name
- SUMO1 activating enzyme subunit 1
- Type
- protein-coding
- Aliases
- AOS1, HSPC140, SUA1, UBLE1A
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
via MyGene.info
Wikidata facts
- Image
- Protein SAE1 PDB 1y8q.png
Show 5 more facts
- HomoloGene ID
- 4019
- exact match
- identifiers.org/ncbigene/10055
- genomic end
- 47713886
- genomic start
- 47616531
- cytogenetic location
- 19q13.32
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Article
4 sectionsContents
- Interactions
- References
- Further reading
- External links
SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.
== Interactions ==