TLR8
Sign in to saveAlso known as CD288, toll like receptor 8, hTLR8, IMD98
protein-coding gene in the species Homo sapiens
In the Vinony graph
Vinony's link graph records 390 inbound references to TLR8, and connects out to PubMed, Ensembl genome database project and CD1.
It sits within the topics Clusters of differentiation, Genes on human chromosome X and Toll-like receptors.
Vinony links it to 5 Wikipedia language editions.
Gene data
TLR8- Name
- toll like receptor 8
- Type
- protein-coding
- Chromosome
- X
- Position
- 12,906,620–12,923,169 (+)
- Aliases
- CD288, IMD98, TLR-8, hTLR8
- Ensembl
- ENSG00000101916
- RefSeq RNA
- NM_016610.4, NM_138636.5
- RefSeq protein
- NP_057694.2, NP_619542.1
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
toll like receptor 8
- Symbol
- TLR8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:12,906,620-12,923,169
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 44054
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51311
- chromosome
- human X chromosome
- genomic end
- 12941288
- genomic start
- 12924739
- cytogenetic location
- Xp22.2
Sources (3)
via Wikidata · CC0