trofosfamide
Sign in to saveTrofosfamide (INN) is a nitrogen mustard alkylating agent. It is sometimes abbreviated "TRO". It has been used in trials to study its effects on ependymoma, medulloblastoma, sarcoma, soft tissue, supratentorial PNET, and recurrent brain tumors.
Research
166 papers- Feasibility and tolerability of trofosfamide and etoposide in progressive glioblastoma.Neuro-oncology advances · 2023
- Trofosfamide in the palliative treatment of cancer: a review of the literature.Onkologie · 2004
- Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma.Journal of cancer research and clinical oncology · 2019
- Trofosfamide: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the oral treatment of cancer.Anti-cancer drugs · 1997
- Genetic effects of cyclophosphamide, ifosfamide and trofosfamide.Mutation research · 1976
via PubMed
Wikidata facts
- Mass
- 322.017
Show 3 more facts
- chemical formula
- C₉H₁₈Cl₃N₂O₂P
- canonical SMILES
- C1CN(P(=O)(OC1)N(CCCl)CCCl)CCCl
- Commons category
- Trofosfamide
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Trofosfamide (INN) is a nitrogen mustard alkylating agent. It is sometimes abbreviated "TRO". It has been used in trials to study its effects on ependymoma, medulloblastoma, sarcoma, soft tissue, supratentorial PNET, and recurrent brain tumors.
==References==
Available in 8 languages
via Wikidata sitelinks · CC0
Connections
tiazofurin
Entity
medication
Entity
digital object identifier
Entity
chemical formula
Entity
chemotherapy
Entity
molar mass
Entity
Q180686
Entity
DNA replication
Entity
tablet
Entity
hydrazine
Entity
cell cycle
Entity
DL-asparagine
Entity
CAS Registry Number
Entity
PubChem
Entity
Anatomical Therapeutic Chemical Classification System
Entity
microtubule
Entity
gene therapy
Entity
arsenic trioxide
Entity
sarcoma
Entity
sex steroid
Entity