temoporfin
Sign in to saveAlso known as meso-tetrahydroxyphenylchlorin, 2,3-dihydro-5,10,15,20-tetra(m-hydroxyphenyl)porphyrin, m-THPC
Temoporfin (INN) is a photosensitizer (based on chlorin) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. It is marketed in the European Union under the brand name Foscan. The U.S. Food and Drug Administration (FDA) declined to approve Foscan in 2000. The EU approved its use in June 2001.
Research
558 papersvia PubMed
Wikidata facts
- Mass
- 680.242355504
Show 3 more facts
- chemical formula
- C₄₄H₃₂N₄O₄
- canonical SMILES
- C1CC2=NC1=C(C3=CC=C(N3)C(=C4C=CC(=N4)C(=C5C=CC(=C2C6=CC(=CC=C6)O)N5)C7=CC(=CC=C7)O)C8=CC(=CC=C8)O)C9=CC(=CC=C9)O
- NCI Thesaurus ID
- C1669
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Article
2 sectionsContents
- References
- Further reading
Temoporfin (INN) is a photosensitizer (based on chlorin) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. It is marketed in the European Union under the brand name Foscan. The U.S. Food and Drug Administration (FDA) declined to approve Foscan in 2000. The EU approved its use in June 2001.
Good results were obtained in 21 of 35 patients treated in Germany.