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Also known as autophagic vacuole, GO:0005776
thumb|The autophagic process is divided into five distinct stages: Initiation, phagophore nucleation, autophagosomal formation (elongation), autophagosome-lysosome fusion (autophagolysosome) and cargo degradation. An autophagosome is a spherical structure with double layer membranes. It is the key structure in macroautophagy, the intracellular degradation system for cytoplasmic contents (e.g., abnormal intracellular proteins, excess or damaged organelles, invading microorganisms). After formation, autophagosomes deliver cytoplasmic components to the lysosomes. The outer membrane of an autophag
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自噬体是在中产生的一种特殊的囊泡,它由细胞内的粗糙内质网或高尔基体膜包裹细胞内源性物质(如由于生理或病理原因损伤的细胞器及其他细胞结构或过量储存的营养物质等)后分离到细胞质中形成。 自噬体直径一般为300-900nm(平均约500nm),其囊泡内常见的内含物包括细胞质基质和某些细胞器(如线粒体、及过氧化物酶体等)。与其他细胞器相比,自噬体的半衰期较短,约为8min。 “自噬体”(英語:autophagosome)一词合成自希腊语词根:“auto”(意为“自身”)、“phagy”(意为“吃”)及“some”(意为“体”)。
Abstract from DBpedia / Wikipedia · CC BY-SA
via Wikidata · CC0
via Wikidata sitelinks · CC0
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).