chlorproethazine
Sign in to saveChlorproethazine, sold under the brand name Neuriplege, is a drug of the phenothiazine group described as a muscle relaxant or tranquilizer which is or has been marketed in Europe as a topical cream for the treatment of muscle pain. It has been associated with photoallergic contact dermatitis. ==Synthesis== Chlorproethazine can be synthesized from a diphenylsulfide derivative. The general scheme is sufficiently flexible to permit the interchange of the order of some of the steps.
Research
16 papers- Phenothiazines boost host control of Mycobacterium avium infection in primary human macrophages.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
- Photocontact allergic and phototoxic studies of chlorproethazine.Photodermatology, photoimmunology & photomedicine · 2008
- Photodermatitis from topical phenothiazines: A case series.Contact dermatitis · 2020
- Contact sensitization to chlorproethazine can induce persistent light reaction and cross-photoreactions to other phenothiazines.Contact dermatitis · 2001
- [Chlorproethazine. Its importance in neurology].La Presse medicale · 1961
via PubMed
Wikidata facts
- Mass
- 346.127
Show 3 more facts
- chemical formula
- C₁₉H₂₃ClN₂S
- canonical SMILES
- CCN(CC)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
- Commons category
- Chlorproethazine
Sources (2)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- Synthesis
- References
Chlorproethazine, sold under the brand name Neuriplege, is a drug of the phenothiazine group described as a muscle relaxant or tranquilizer which is or has been marketed in Europe as a topical cream for the treatment of muscle pain. It has been associated with photoallergic contact dermatitis. ==Synthesis== Chlorproethazine can be synthesized from a diphenylsulfide derivative. The general scheme is sufficiently flexible to permit the interchange of the order of some of the steps.
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