iprindolo

Key facts

Drug.Watchedfields

changed

Drug.verifiedrevid

439569389

Drug.IUPAC_name

3-(6,7,8,9,10,11-hexahydro-5H-cycloocta[b]indol-5-yl)-N,N-dimethylpropan-1-amine

Drug.image

Iprindole.svg

Drug.image_class

skin-invert-image

Drug.width

200px

Drug.image2

Iprindole molecule ball.png

Drug.image_class2

bg-transparent

Drug.width2

200px

Drug.tradename

Prondol, Galatur, Tertran

Drug.legal_status

Rx-only

Drug.routes_of_administration

Oral

Drug.metabolism

Hepatic

Drug.elimination_half life

52.5 hours

Drug.excretion

Urine, Feces

Drug.CAS_number

5560-72-5

Drug.CAS_supplemental

20432-64-8 (hydrochloride)

Drug.ATC_prefix

N06

via Wikipedia infobox

Chemical data

Formula

C19H28N2

Molecular weight

284.4 g/mol

IUPAC name

3-(6,7,8,9,10,11-hexahydrocycloocta[b]indol-5-yl)-N,N-dimethylpropan-1-amine

SMILES

CN(C)CCCN1C2=C(CCCCCC2)C3=CC=CC=C31

InChIKey

PLIGPBGDXASWPX-UHFFFAOYSA-N

XLogP

4.6

Polar surface area

8.2 Ų

H-bond donors

0

H-bond acceptors

1

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

Indications

major depressive disorder

via ChEMBL · EBI

• Metabolism of some "second"- and "fourth"-generation antidepressants: iprindole, viloxazine, bupropion, mianserin, maprotiline, trazodone, nefazodone, and venlafaxine.Cellular and molecular neurobiology · 1999
• Antidepressant overdosage.Drugs · 1982
• Iprindole: a cornerstone in the neurobiological investigation of antidepressant treatments.Modern problems of pharmacopsychiatry · 1982
• The effects of iprindole on noradrenergic transmission in the rat anococcygeus muscle.Naunyn-Schmiedeberg's archives of pharmacology · 1983
• Effects of neonatally administered iprindole on adult behaviors of rats.Pharmacology, biochemistry, and behavior · 1996

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

284.225

via Wikidata · CC0