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ketorolac

Ketorolac, sold under the brand name Toradol, Acular and Sprix, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain. Specifically it is recommended for moderate to severe pain. Recommended duration of treatment is less than six days, and in Switzerland not more than seven days (parenterally two days). It is used by mouth, by nose, by injection into a vein or muscle, and as eye drops. Effects begin within an hour and last for up to eight hours. Ketorolac also has antipyretic (fever-reducing) properties.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 461740251
Drug.image: Ketorolac.svg
Drug.image_class: skin-invert-image
Drug.chirality: Racemic mixture
Drug.caption: Above: molecular structure of ketorolac Below: 3D representation of a ketorolac molecule
Drug.image2: Ketorolac 3D.png
Drug.image_class2: bg-transparent
Drug.tradename: Toradol, Acular, Sprix, others
Drug.MedlinePlus: a693001
Drug.DailyMedID: Ketorolac
Drug.pregnancy_AU: C
Drug.routes_of_administration: By mouth, under the tongue, intramuscular, intravenous, eye drops, nasal spray
Drug.ATC_prefix: M01
Drug.ATC_suffix: AB15
Drug.legal_AU: S4
Drug.legal_CA: Rx-only

via Wikipedia infobox

Article

8 sections

Contents

Medical uses
Contraindications
Adverse effects
Interactions
Mechanism of action
History
References
Further reading

Common side effects include sleepiness, dizziness, abdominal pain, swelling, and nausea. Serious side effects may include stomach bleeding, kidney failure, heart attacks, bronchospasm, heart failure, and anaphylaxis. Use is not recommended during the last part of pregnancy or during breastfeeding. Ketorolac works by blocking cyclooxygenase 1 and 2 (COX1 and COX2), thereby decreasing production of prostaglandins.