KLRB1
Sign in to saveAlso known as CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A, killer cell lectin like receptor B1
Killer cell lectin-like receptor subfamily B, member 1, also known as KLRB1, NKR-P1A or CD161 (cluster of differentiation 161), is a human gene.
In the Vinony graph
Vinony's link graph records 365 inbound references to KLRB1, and connects out to PubMed, Ensembl genome database project and CD1.
It is catalogued under topics including Clusters of differentiation and Genes on human chromosome 12.
Vinony links it to 6 Wikipedia language editions.
Gene data
KLRB1- Name
- killer cell lectin like receptor B1
- Type
- protein-coding
- Position
- 9,593,888–9,607,949 (−)
- Aliases
- CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
- Ensembl
- ENSG00000111796
- RefSeq RNA
- NM_002258.3
- RefSeq protein
- NP_002249.1
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
killer cell lectin like receptor B1
- Symbol
- KLRB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:9,593,888-9,607,949
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 84369
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3820
- genomic end
- 9607916
- genomic start
- 9747147
- chromosome
- human chromosome 12
- cytogenetic location
- 12p13.31
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Killer cell lectin-like receptor subfamily B, member 1, also known as KLRB1, NKR-P1A or CD161 (cluster of differentiation 161), is a human gene.
== Function ==
Excerpted from Wikipedia’s “KLRB1” article, available under the CC BY-SA 4.0 licence.