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mebanazine
Sign in to saveMebanazine (trade name Actomol) is a monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was previously used as an antidepressant in the 1960s, but has since been withdrawn due to hepatotoxicity.
Chemical data
- Formula
- C8H12N2
- Molecular weight
- 136.19 g/mol
- IUPAC name
- 1-phenylethylhydrazine
- SMILES
- CC(C1=CC=CC=C1)NN
- InChIKey
- HHRZAEJMHSGZNP-UHFFFAOYSA-N
- XLogP
- 0.9
- Polar surface area
- 38.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 136.100048
- Has use
- medication
Show 3 more facts
- Commons category
- Mebanazine
- chemical formula
- C₈H₁₂N₂
- canonical SMILES
- CC(C1=CC=CC=C1)NN
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Mebanazine (trade name Actomol) is a monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was previously used as an antidepressant in the 1960s, but has since been withdrawn due to hepatotoxicity.
Mebanazine in animals is claimed to be a more potent MAOI than pheniprazine with a greater therapeutic index. == See also == Hydrazine (antidepressant)
Excerpted from Wikipedia’s “mebanazine” article, available under the CC BY-SA 4.0 licence.
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