MYO1E
Sign in to saveAlso known as FSGS6, HuncM-IC, MYO1C, myosin IE
Myosin-Ie (Myo1e) is a protein that in humans is encoded by the MYO1E gene.
Gene data
MYO1E- Name
- myosin IE
- Type
- protein-coding
- Aliases
- FSGS6, HuncM-IC, MYO1C
This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012].
via MyGene.info
Gene · Ensembl
myosin IE
- Symbol
- MYO1E
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:59,132,409-59,373,121
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 55864
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4643
- genomic end
- 59372871
- genomic start
- 59427113
- chromosome
- human chromosome 15
- cytogenetic location
- 15q22.2
- genetic association
- focal segmental glomerulosclerosis
- expressed in
- ascending aorta
via Wikidata · CC0
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Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Myosin-Ie (Myo1e) is a protein that in humans is encoded by the MYO1E gene.
Myosin-Ie is a long tailed myosin. It contains an N-terminal motor domain, an IQ motif, a TH1 domain containing a plecstrin homology (PH) domain, a proline rich TH2 domain, and an SH3 domain.
Excerpted from Wikipedia’s “MYO1E” article, available under the CC BY-SA 4.0 licence.