'''cAMP-specific 3',5'-cyclic phosphodiesterase 4B' is an enzyme that in humans is encoded by the PDE4B'' gene.
'''cAMP-specific 3',5'-cyclic phosphodiesterase 4B' is an enzyme that in humans is encoded by the PDE4B'' gene.
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).