Structure via PubChem · Public domain (PubChem)
pheniprazine
Sign in to savePheniprazine, formerly sold under the brand names Catron and Cavodil, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine group that was used as an antidepressant to treat depression in the 1960s. It was also used in the treatment of angina pectoris and schizophrenia. Pheniprazine has been largely discontinued due to toxicity concerns such as jaundice, amblyopia, and optic neuritis.
Chemical data
- Formula
- C9H14N2
- Molecular weight
- 150.22 g/mol
- IUPAC name
- 1-phenylpropan-2-ylhydrazine
- SMILES
- CC(CC1=CC=CC=C1)NN
- InChIKey
- VXTWEDPZMSVFEF-UHFFFAOYSA-N
- XLogP
- 1.3
- Polar surface area
- 38.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 150.115698
- Has use
- medication
Show 3 more facts
- chemical formula
- C₉H₁₄N₂
- canonical SMILES
- CC(CC1=CC=CC=C1)NN
- Commons category
- Pheniprazine
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Pharmacology
- Chemistry
- Society and culture
- Names
- References
Pheniprazine, formerly sold under the brand names Catron and Cavodil, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine group that was used as an antidepressant to treat depression in the 1960s. It was also used in the treatment of angina pectoris and schizophrenia. Pheniprazine has been largely discontinued due to toxicity concerns such as jaundice, amblyopia, and optic neuritis.
==Pharmacology== Pheniprazine is a monoamine oxidase inhibitor (MAOI).
Excerpted from Wikipedia’s “pheniprazine” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0