Chemical data
- Formula
- C5H7N3O5
- Molecular weight
- 189.13 g/mol
- IUPAC name
- (2S)-2-azaniumyl-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoate
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,568 papers- Quisqualic acid-induced neurotoxicity is protected by NMDA and non-NMDA receptor antagonists.Neuroscience letters · 1992
- Posttraumatic syringomyelia.Journal of neurosurgery. Spine · 2011
- Quisqualic acid modulates kainate responses in cultured cerebellar granule cells.Journal of neurochemistry · 1989
- Quisqualic acid analogues: synthesis of beta-heterocyclic 2-aminopropanoic acid derivatives and their activity at a novel quisqualate-sensitized site.
Article · 中文
使君子氨酸（英語：Quisqualic acid）是一种AMPA受体、和I型代谢型谷氨酸受体的激动剂，也是已知最强的AMPA受体激动剂。由于它具有，被广泛用于神经科学研究中，选择性地破坏大脑中的神经元或脊髓。使君子氨酸存在于使君子科物种的种子中。一项由美国农业部进行的研究显示，使君子氨酸也存在于天竺葵属的花瓣中，并能使其天敌甲壳虫神经系统瘫痪。其作用机理为，使君子氨酸可被视为L-谷氨酸的类似物，可以作为昆虫神经肌肉结和哺乳动物中枢神经系统的神经递质。
Abstract from DBpedia / Wikipedia · CC BY-SA