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GeneQ18031123· pop 5· linked from 697 articles

Also known as CD241, RH2, RH50A, Rh50, Rh50GP, SLC42A1, OHS, OHST

Rh-associated glycoprotein (RHAG) is an ammonia transporter protein that in humans is encoded by the RHAG gene. RHAG has also recently been designated CD241 (cluster of differentiation 241). Mutations in the RHAG gene can cause stomatocytosis.

Gene data

RHAG
Name
Rh associated glycoprotein
Type
protein-coding
Aliases
CD241, OHS, OHST, RH2, RH50A, RHNR, Rh50, Rh50GP, SLC42A1

The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009].

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Wikidata facts

Show 6 more facts
HomoloGene ID
68045
genomic end
49636839
genomic start
49605175
cytogenetic location
6p12.3
Commons category
RHAG
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Article

7 sections
Contents
  • Function
  • Clinical diagnostic
  • Interactions
  • See also
  • References
  • Further reading
  • External links

Rh-associated glycoprotein (RHAG) is an ammonia transporter protein that in humans is encoded by the RHAG gene. RHAG has also recently been designated CD241 (cluster of differentiation 241). Mutations in the RHAG gene can cause stomatocytosis.

== Function ==

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