riluzolo

Chemical data

Formula

C8H5F3N2OS

Molecular weight

234.2 g/mol

IUPAC name

6-(trifluoromethoxy)-1,3-benzothiazol-2-amine

SMILES

C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N

InChIKey

FTALBRSUTCGOEG-UHFFFAOYSA-N

XLogP

3.6

Polar surface area

76.4 Ų

H-bond donors

1

H-bond acceptors

7

Formal charge

0

via PubChem

• Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).The Cochrane database of systematic reviews · 2012
• The pharmacology and mechanism of action of riluzole.Neurology · 1996
• Riluzole for the treatment of amyotrophic lateral sclerosis.Neurodegenerative disease management · 2020
• A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group.The New England journal of medicine · 1994
• Riluzole.Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases · 2000

via PubMed