Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Within Vinony's link graph, riluzol is referenced by 547 other articles, and connects out to ginkgolide, γ-aminobutyric acid and valproic acid.
It is catalogued under topics including Benzothiazoles, Drugs with non-standard legal status and Drugs with unknown mechanisms of action.
Its subject is documented across 26 Wikipedia language editions.
Chemical data
- Formula
- C8H5F3N2OS
- Molecular weight
- 234.2 g/mol
- IUPAC name
- 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
- SMILES
- C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
- InChIKey
- FTALBRSUTCGOEG-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 76.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1995
- Admin. routes
- oral
- Indications
- post-traumatic stress disorder, autism spectrum disorder, cutaneous melanoma, obsessive-compulsive disorder
via ChEMBL · EBI
Research
2,265 papers- Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).The Cochrane database of systematic reviews · 2012
- The pharmacology and mechanism of action of riluzole.Neurology · 1996
- Riluzole for the treatment of amyotrophic lateral sclerosis.Neurodegenerative disease management · 2020
- A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group.The New England journal of medicine · 1994
- Riluzole.Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases · 2000
via PubMed
Wikidata facts
- Mass
- 234.007468
- Has use
- medication
Show 5 more facts
- chemical formula
- C₈H₅F₃N₂OS
- medical condition treated
- ALS
- canonical SMILES
- C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
- defined daily dose
- 0.1
- Commons category
- Riluzole
Sources (8)
via Wikidata · CC0
Article · Nederlands
Riluzol (merknaam: Rilutek) is het enige geregistreerde medicijn dat bewezen effectief is bij de behandeling van amyotrofe laterale sclerose (ALS).
Abstract from DBpedia / Wikipedia · CC BY-SA
Gallery (3)
Connections
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