Tropomodulin
Sign in to savethumb|Tropomodulin Tropomodulin (TMOD) is a protein which binds and caps the minus end of actin (the "pointed" end), regulating the length of actin filaments in muscle and non-muscle cells.
In the Vinony graph
Vinony's link graph records 274 inbound references to Tropomodulin, and connects out to hair keratin, cytokeratin and protein.
It is catalogued under the topic Tropomodulin.
Vinony links it to 5 Wikipedia language editions.
~7 min read
Encyclopedic overview
4 sectionsContents
- Genes
- References
- Further reading
- External links
thumb|Tropomodulin Tropomodulin (TMOD) is a protein which binds and caps the minus end of actin (the "pointed" end), regulating the length of actin filaments in muscle and non-muscle cells.
The protein functions by physically blocking the spontaneous dissociation of ADP-bound actin monomers from the minus end of the actin fibre. This, along with plus end capping proteins, such as capZ stabilise the structure of the actin filament. End capping is particularly important when long-lived actin filaments are necessary, for example: in myofibrils. Inhibition of tropomodulin capping activity leads to dramatic increase in thin filament length from its pointed end.
Excerpted from Wikipedia’s “Tropomodulin” article, available under the CC BY-SA 4.0 licence.