vigabatrine

Also known as CPP-109, MDL-71754, Sabril®, gamma-vinyl-gamma-aminobutyric acid, gamma-vinyl GABA, GVG, 4-Amino-5-hexenoic acid, gamma-Vinyl-gamma-aminobutyric acid

composé chimique

Key facts

Drug.Watchedfields: changed
Drug.verifiedrevid: 470630102
Drug.image: Vigabatrin.svg
Drug.image_class: skin-invert-image
Drug.width: 200px
Drug.image2: Vigabatrin ball-and-stick.png
Drug.image_class2: bg-transparent
Drug.width2: 200px
Drug.tradename: Vigafyde, Sabril, others
Drug.MedlinePlus: a610016
Drug.DailyMedID: Vigabatrin
Drug.pregnancy_AU: D
Drug.routes_of_administration: By mouth
Drug.class: Anticonvulsant; GABA-T inhibitor
Drug.ATC_prefix: N03
Drug.ATC_suffix: AG04
Drug.legal_AU: S4
Drug.legal_BR: C1

via Wikipedia infobox

Chemical data

Formula: C6H11NO2
Molecular weight: 129.16 g/mol
IUPAC name: 4-aminohex-5-enoic acid
SMILES: C=CC(CCC(=O)O)N
InChIKey: PJDFLNIOAUIZSL-UHFFFAOYSA-N
XLogP: -2.2
Polar surface area: 63.3 Å²
H-bond donors: 2
H-bond acceptors: 3
Formal charge: 0

via PubChem

Research

2,705 papers

Vigabatrin.Epilepsia · 1999
Vigabatrin.The Annals of pharmacotherapy · 1993
The vigabatrin-associated brain abnormalities on MRI and their differential diagnosis.Clinical radiology · 2024
Vigabatrin.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2007
Vigabatrin.Developmental medicine and child neurology · 2001

via PubMed

Wikidata facts

Mass: 129.078979

Show 5 more facts

chemical formula: C₆H₁₁NO₂
canonical SMILES: C=CC(CCC(=O)O)N
Commons category: Vigabatrin
World Health Organisation international non-proprietary name: vigabatrin
defined daily dose: 2

Sources (6)

via Wikidata · CC0

Article · Français

Le vigabatrine est un anticonvulsant qui inhibe le catabolisme de GABA. Il a une structure similaire au GABA, mais n'est pas un agoniste des récepteurs.

Abstract from DBpedia / Wikipedia · CC BY-SA