Vigabatrin

Also known as CPP-109, MDL-71754, Sabril®, gamma-vinyl-gamma-aminobutyric acid, gamma-vinyl GABA, GVG, 4-Amino-5-hexenoic acid, gamma-Vinyl-gamma-aminobutyric acid

Vigabatrin, sold under the brand name Vigafyde among others, is a medication used in the management and treatment of infantile spasms and refractory complex partial seizures.

In the Vinony graph

Vinony's link graph records 217 inbound references to Vigabatrin, and connects out to valproic acid, γ-aminobutyric acid and West syndrome.

It sits within the topics Alkene derivatives, Anticonvulsants and Drugboxes which contain changes to watched fields.

Vinony links it to 19 Wikipedia language editions.

Key facts

Drug.Watchedfields: changed
Drug.verifiedrevid: 470630102
Drug.image: Vigabatrin.svg
Drug.image_class: skin-invert-image
Drug.width: 200px
Drug.image2: Vigabatrin ball-and-stick.png
Drug.image_class2: bg-transparent
Drug.width2: 200px
Drug.tradename: Vigafyde, Sabril, others
Drug.MedlinePlus: a610016
Drug.DailyMedID: Vigabatrin
Drug.pregnancy_AU: D
Drug.routes_of_administration: By mouth
Drug.class: Anticonvulsant; GABA-T inhibitor
Drug.ATC_prefix: N03
Drug.ATC_suffix: AG04
Drug.legal_AU: S4
Drug.legal_BR: C1

via Wikipedia infobox

Chemical data

Formula: C6H11NO2
Molecular weight: 129.16 g/mol
IUPAC name: 4-aminohex-5-enoic acid
SMILES: C=CC(CCC(=O)O)N
InChIKey: PJDFLNIOAUIZSL-UHFFFAOYSA-N
XLogP: -2.2
Polar surface area: 63.3 Å²
H-bond donors: 2
H-bond acceptors: 3
Formal charge: 0

via PubChem

Research

2,705 papers

Vigabatrin.Epilepsia · 1999
Vigabatrin.The Annals of pharmacotherapy · 1993
The vigabatrin-associated brain abnormalities on MRI and their differential diagnosis.Clinical radiology · 2024
Vigabatrin.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2007
Vigabatrin.Developmental medicine and child neurology · 2001

via PubMed