Structure via PubChem · Public domain (PubChem)
viminol
Sign in to saveViminol (marketed under the brandname Dividol) is an opioid analgesic developed by a team at the drug company Zambon in the 1960s. Viminol is based on the α-pyrryl-2-aminoethanol structure, unlike any other class of opioids.
In the Vinony graph
Within Vinony's link graph, viminol is referenced by 818 other articles, and connects out to (+)-catechin, butorphanol and OPRM1.
Vinony files it under 2-Chlorophenyl compounds, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C21H31ClN2O
- Molecular weight
- 362.9 g/mol
- IUPAC name
- 1-[1-[(2-chlorophenyl)methyl]pyrrol-2-yl]-2-[di(butan-2-yl)amino]ethanol
- SMILES
- CCC(C)N(CC(C1=CC=CN1CC2=CC=CC=C2Cl)O)C(C)CC
- InChIKey
- ZILPIBYANAFGMS-UHFFFAOYSA-N
- XLogP
- 4.8
- Polar surface area
- 28.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Fever, pain
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 362.212
Show 3 more facts
- canonical SMILES
- CCC(C)N(CC(C1=CC=CN1CC2=CC=CC=C2Cl)O)C(C)CC
- chemical formula
- C₂₁H₃₁ClN₂O
- Commons category
- Viminol
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Side effects
- Related compounds
- References
Viminol (marketed under the brandname Dividol) is an opioid analgesic developed by a team at the drug company Zambon in the 1960s. Viminol is based on the α-pyrryl-2-aminoethanol structure, unlike any other class of opioids.
Viminol has both antitussive (cough suppressing) and analgesic (pain reducing) effects. Viminol has additional effects similar to other opioids including sedation and euphoria. It has six different stereoisomers which have varying properties. Four are inactive, but the 1S-(R,R)-disecbutyl isomer is a μ-opioid full agonist around 5.5 times more potent than morphine and the 1S-(S,S)-disecbutyl isomer is an antagonist. Since viminol is supplied as a racemic mixture of isomers, the overall effect is a mixed agonist–antagonist profile similar to that of opioids such as pentazocine, although with somewhat fewer side effects.
Excerpted from Wikipedia’s “viminol” article, available under the CC BY-SA 4.0 licence.