CELSR3

Also known as CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1, ADGRC3, cadherin EGF LAG seven-pass G-type receptor 3

Cadherin EGF LAG seven-pass G-type receptor 3 is a protein that in humans is encoded by the CELSR3 gene.

In the Vinony graph

Within Vinony's link graph, CELSR3 is referenced by 488 other articles, and connects out to PubMed, Ensembl genome database project and cell surface receptor.

Vinony files it under Adhesion G protein-coupled receptors, Genes on human chromosome 3 and G protein-coupled receptors.

Its subject is documented across 5 Wikipedia language editions.

Gene data

CELSR3

Name: cadherin EGF LAG seven-pass G-type receptor 3
Type: protein-coding
Position: 48,636,463–48,662,886 (−)
Aliases: ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1
Ensembl: ENSG00000008300
RefSeq RNA: NM_001407.3
RefSeq protein: NP_001398.2

This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013].