Structure via PubChem · Public domain (PubChem)
cyclopentamine
Sign in to saveAlso known as (RS)-1-cyclopentyl-N-methylpropan-2-amine, (RS)-cyclopentamine
Cyclopentamine (trade names Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos, among others) is a sympathomimetic and vasoconstrictor drug of the alkylamine family and related to the arylalkylamines. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia, but has now been largely discontinued.
In the Vinony graph
Within Vinony's link graph, cyclopentamine is referenced by 1,543 other articles, and connects out to D-methamphetamine, N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine and monoamine releasing agent.
Vinony files it under Cycloalkylalkylamines, Cyclopentyl compounds and Decongestants.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C9H19N
- Molecular weight
- 141.25 g/mol
- IUPAC name
- 1-cyclopentyl-N-methylpropan-2-amine
- SMILES
- CC(CC1CCCC1)NC
- InChIKey
- HFXKQSZZZPGLKQ-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 12 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Nasal congestion
via ChEMBL · EBI
Wikidata facts
- Mass
- 141.152
- Has use
- medication
Show 4 more facts
- World Health Organisation international non-proprietary name
- cyclopentamine
- canonical SMILES
- CC(CC1CCCC1)NC
- chemical formula
- C₉H₁₉N
- Commons category
- Cyclopentamine
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Pharmacology
- Chemistry
- See also
- References
Cyclopentamine (trade names Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos, among others) is a sympathomimetic and vasoconstrictor drug of the alkylamine family and related to the arylalkylamines. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia, but has now been largely discontinued.
== Pharmacology == Cyclopentamine acts as a releasing agent of the catecholamine neurotransmitters norepinephrine (noradrenaline), epinephrine (adrenaline), and dopamine. Its effects on norepinephrine and epinephrine mediate its decongestant effects, while its effects on all three neurotransmitters are responsible for its stimulant properties. When ingested orally in sufficient quantities, cyclopentamine produces similar effects to amphetamine, methamphetamine, and propylhexedrine.
Excerpted from Wikipedia’s “cyclopentamine” article, available under the CC BY-SA 4.0 licence.