D-(-)-mannitol
Sign in to saveMannitol is a type of sugar alcohol used as a sweetener and medication. It is used as a low-calorie sweetener as it is poorly absorbed by the intestines. As a medication, it is used to decrease pressure in the eyes, as in glaucoma, and to lower increased intracranial pressure. Medically, it is given by injection or inhalation. Effects typically begin within 15 minutes and last up to 8 hours.
Key facts
- Drug.verifiedrevid
- 456482551
- Drug.image
- D-Mannitol structure.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Mannitol-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Osmitrol, Bronchitol, others
- Drug.DailyMedID
- Mannitol
- Drug.pregnancy_AU
- B2
- Drug.routes_of_administration
- Intravenous, by mouth, inhalation
- Drug.ATC_prefix
- A06
- Drug.ATC_suffix
- AD16
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.bioavailability
- ~7%
- Drug.metabolism
- Liver, negligible
- Drug.elimination_half life
- 100 minutes
- Drug.excretion
- Kidney: 90%
via Wikipedia infobox
Article
20 sectionsContents
- Uses
- Medical uses
- Injected
- Inhaled
- Oral
- Food
- Analytical chemistry
- Other
- Contraindications
- Chemistry
- Production
- Industrial synthesis
- Biosyntheses
- Natural extraction
- History
- Controversy
- Compendial status
- See also
- References
- External links
Mannitol is a type of sugar alcohol used as a sweetener and medication. It is used as a low-calorie sweetener as it is poorly absorbed by the intestines. As a medication, it is used to decrease pressure in the eyes, as in glaucoma, and to lower increased intracranial pressure. Medically, it is given by injection or inhalation. Effects typically begin within 15 minutes and last up to 8 hours.
Common side effects from medical use include electrolyte problems and dehydration. Other serious side effects may include worsening heart failure and kidney problems. It is unclear if use is safe in pregnancy. Mannitol is in the osmotic diuretic family of medications and works by pulling fluid from the brain and eyes.