
Also known as WY-45233, 1-[2-(dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol, 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, O-desmethylvenlafaxine, ODV, (±)-desvenlafaxine
Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat depression. It is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class and is taken by mouth. It is recommended that the need for further treatment be occasionally reassessed. Studies have shown similar effectiveness compared to its parent compound venlafaxine.
Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat depression. It is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class and is taken by mouth. It is recommended that the need for further treatment be occasionally reassessed. Studies have shown similar effectiveness compared to its parent compound venlafaxine.
Common side effects include dizziness, trouble sleeping, increased sweating, constipation, sleepiness, anxiety, and sexual problems. Serious side effects may include suicide in those under the age of 25, serotonin syndrome, bleeding, mania, and high blood pressure. There is a high risk of withdrawal syndrome which may occur if the dose is decreased or the medication is completely stopped. It is unclear if use during pregnancy or breastfeeding is safe.
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