Structure via PubChem · Public domain (PubChem)
اپروبماید
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Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol). It is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination. Eprobemide differs from moclobemide only in the linker that connects the morpholine fragment with the chlorobenzamide — moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.
Chemical data
- Formula
- C14H19ClN2O2
- Molecular weight
- 282.76 g/mol
- IUPAC name
- 4-chloro-N-(3-morpholin-4-ylpropyl)benzamide
- SMILES
- C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
- InChIKey
- YYFGRAGNYHYWEZ-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 282.114
Show 3 more facts
- Commons category
- Eprobemide
- chemical formula
- C₁₄H₁₉ClN₂O₂
- canonical SMILES
- C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
Sources (2)
via Wikidata · CC0