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اپروبماید

Structure via PubChem · Public domain (PubChem)

EntityQ4086013· pop 6· linked from 451 articles

اپروبماید

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Also known as Бефол

Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol). It is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination. Eprobemide differs from moclobemide only in the linker that connects the morpholine fragment with the chlorobenzamide — moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.

Chemical data

Formula
C14H19ClN2O2
Molecular weight
282.76 g/mol
IUPAC name
4-chloro-N-(3-morpholin-4-ylpropyl)benzamide
SMILES
C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
InChIKey
YYFGRAGNYHYWEZ-UHFFFAOYSA-N
XLogP
1.8
Polar surface area
41.6 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
282.114
Show 3 more facts
Commons category
Eprobemide
chemical formula
C₁₄H₁₉ClN₂O₂
canonical SMILES
C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
Sources (2)

via Wikidata · CC0

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via Wikidata sitelinks · CC0