Structure via PubChem · Public domain (PubChem)
fluanisone
Sign in to saveFluanisone is a typical antipsychotic and sedative of the butyrophenone chemical class. It is used in the treatment of schizophrenia and mania. It is also a component (along with fentanyl) of the injectable veterinary formulation fentanyl/fluanisone (Hypnorm) where it is used for rodent analgesia during short surgical procedures.
In the Vinony graph
Within Vinony's link graph, fluanisone is referenced by 585 other articles, and connects out to fluphenazine, zuclopenthixol and flupentixol.
Vinony files it under 2-Methoxyphenyl compounds, 4-Fluorophenyl compounds and Butyrophenone antipsychotics.
Its subject is documented across 4 Wikipedia language editions.
Chemical data
- Formula
- C21H25FN2O2
- Molecular weight
- 356.4 g/mol
- IUPAC name
- 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one
- SMILES
- COC1=CC=CC=C1N2CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F
- InChIKey
- IRYFCWPNDIUQOW-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 32.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- psychosis
via ChEMBL · EBI
Research
98 papers- Reversal of fentanyl/fluanisone neuroleptanalgesia in the rabbit using mixed agonist/antagonist opioids.Laboratory animals · 1989
- Comparing anesthesia with isoflurane and fentanyl/fluanisone/midazolam in a rat model of cardiac arrest.Journal of applied physiology (Bethesda, Md. : 1985) · 2017
- Midazolam and fentanyl-fluanisone: assessment of anaesthetic effects in laboratory rodents and rabbits.Laboratory animals · 1984
- Effects of the neuroleptanalgesic fentanyl-fluanisone (Hypnorm) on spike-wave discharges in epileptic rats.Pharmacology, biochemistry, and behavior · 1994
- The effects of post-operative oxygen supply on blood oxygenation and acid-base status in rats anaesthetized with fentanyl/fluanisone and midazolam.PloS one · 2021
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 356.19
Show 3 more facts
- chemical formula
- C₂₁H₂₅FN₂O₂
- canonical SMILES
- COC1=CC=CC=C1N2CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F
- Commons category
- Fluanisone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Fluanisone is a typical antipsychotic and sedative of the butyrophenone chemical class. It is used in the treatment of schizophrenia and mania. It is also a component (along with fentanyl) of the injectable veterinary formulation fentanyl/fluanisone (Hypnorm) where it is used for rodent analgesia during short surgical procedures.
==See also== Enciprazine BMY-14802 Azaperone
Excerpted from Wikipedia’s “fluanisone” article, available under the CC BY-SA 4.0 licence.