LAIR2
Sign in to saveAlso known as CD306, leukocyte associated immunoglobulin like receptor 2
Leukocyte-associated immunoglobulin-like receptor 2 is a protein that in humans is encoded by the LAIR2 gene.
In the Vinony graph
Vinony's link graph records 357 inbound references to LAIR2, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 6 Wikipedia language editions.
Gene data
LAIR2- Name
- leukocyte associated immunoglobulin like receptor 2
- Type
- protein-coding
- Position
- 54,497,879–54,510,694 (+)
- Aliases
- CD306
- Ensembl
- ENSG00000277335
- RefSeq RNA
- NM_002288.6, NM_021270.5, XM_011526961.3, XM_054320988.1, XM_054329681.1
- RefSeq protein
- NP_002279.2, NP_067154.1, XP_011525263.1, XP_054176963.1, XP_054185656.1
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013].
Gene Ontology
Biological process
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
leukocyte associated immunoglobulin like receptor 2
- Symbol
- LAIR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:54,497,879-54,510,694
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 88663
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3904
- chromosome
- human chromosome 19
- genomic start
- 55009100
- genomic end
- 55021897
- cytogenetic location
- 19q13.42
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Leukocyte-associated immunoglobulin-like receptor 2 is a protein that in humans is encoded by the LAIR2 gene.
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “LAIR2” article, available under the CC BY-SA 4.0 licence.