nemonapride
Sign in to saveAlso known as (±)-nemonapride, cis-nemonapride, Emilace, rel-5-chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide
Nemonapride, also previously known as emonapride and sold under the brand name Emilace, is an atypical antipsychotic which is used in the treatment of schizophrenia. It is taken by mouth.
Research
314 papers- [3H]nemonapride binding in human caudate and putamen.Brain research bulletin · 1997
- Associations between side effects of nemonapride and plasma concentrations of the drug and prolactin.Progress in neuro-psychopharmacology & biological psychiatry · 2002
- Multiple [3H]-nemonapride binding sites in calf brain.Naunyn-Schmiedeberg's archives of pharmacology · 1997
- Nemonapride for the treatment of schizophrenia.The American journal of psychiatry · 1997
- High-performance liquid chromatographic determination of nemonapride and desmethylnemonapride in human plasma using an electrochemical detection.Journal of chromatography. B, Biomedical sciences and applications · 1998
via PubMed
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Encyclopedic overview
14 sectionsContents
- Medical uses
- Available forms
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Structure and stereochemistry
- History
- Society and culture
- Names
- Availability
- See also
- References
Nemonapride, also previously known as emonapride and sold under the brand name Emilace, is an atypical antipsychotic which is used in the treatment of schizophrenia. It is taken by mouth.
Side effects of nemonapride include akathisia, dystonia, hypokinesia, tremor, hypersalivation, and hyperprolactinemia, among others. The drug acts as a dopamine D2, D3, and D4 receptor antagonist. To a lesser extent, it is also a serotonin 5-HT1A receptor partial agonist. Structurally, nemonapride is a benzamide derivative and is related to sulpiride and other benzamides.
Excerpted from Wikipedia’s “nemonapride” article, available under the CC BY-SA 4.0 licence.
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