ネモナプリド
Sign in to saveAlso known as (±)-nemonapride, cis-nemonapride, Emilace, rel-5-chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide
Nemonapride, also previously known as emonapride and sold under the brand name Emilace, is an atypical antipsychotic which is used in the treatment of schizophrenia. It is taken by mouth.
In the Vinony graph
Vinony's link graph records 618 inbound references to ネモナプリド, and connects out to fluphenazine, zuclopenthixol and pipotiazine.
It is catalogued under topics including 5-HT1A agonists, Atypical antipsychotics and Benzamides.
Vinony links it to 8 Wikipedia language editions.
Research
314 papers- [3H]nemonapride binding in human caudate and putamen.Brain research bulletin · 1997
- Associations between side effects of nemonapride and plasma concentrations of the drug and prolactin.Progress in neuro-psychopharmacology & biological psychiatry · 2002
- Multiple [3H]-nemonapride binding sites in calf brain.Naunyn-Schmiedeberg's archives of pharmacology · 1997
- Nemonapride for the treatment of schizophrenia.The American journal of psychiatry · 1997
- High-performance liquid chromatographic determination of nemonapride and desmethylnemonapride in human plasma using an electrochemical detection.Journal of chromatography. B, Biomedical sciences and applications · 1998
via PubMed
Wikidata facts
- Mass
- 387.171354752
- Has use
- medication
Show 5 more facts
- canonical SMILES
- O=C(NC1CCN(CC=2C=CC=CC2)C1C)C=3C=C(Cl)C(=CC3OC)NC
- isomeric SMILES
- C(N[C@H]1[C@@H](C)N(CC2=CC=CC=C2)CC1)(=O)C3=C(OC)C=C(NC)C(Cl)=C3
- subject has role
- dopamine antagonist
- chemical formula
- C₂₁H₂₆ClN₃O₂
- Commons category
- Nemonapride
Sources (2)
via Wikidata · CC0
Article · 日本語
ネモナプリド (Nemonapride) は、ベンズアミド系の抗精神病薬。分子式は C21H26ClN3O2。融点150–153℃。水に不溶。強力なドーパミンD2受容体遮断作用を示し、統合失調症などの治療に用いられる。 アステラス製薬からエミレースなどの商品名で販売されている。
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 8 languages
via Wikidata sitelinks · CC0