Nemonaprida
Sign in to saveAlso known as (±)-nemonapride, cis-nemonapride, Emilace, rel-5-chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide
Nemonapride, also previously known as emonapride and sold under the brand name Emilace, is an atypical antipsychotic which is used in the treatment of schizophrenia. It is taken by mouth.
In the Vinony graph
Within Vinony's link graph, Nemonaprida is referenced by 618 other articles, and connects out to fluphenazine, zuclopenthixol and pipotiazine.
Vinony files it under 5-HT1A agonists, Atypical antipsychotics and Benzamides.
Its subject is documented across 8 Wikipedia language editions.
Research
314 papers- [3H]nemonapride binding in human caudate and putamen.Brain research bulletin · 1997
- Associations between side effects of nemonapride and plasma concentrations of the drug and prolactin.Progress in neuro-psychopharmacology & biological psychiatry · 2002
- Multiple [3H]-nemonapride binding sites in calf brain.Naunyn-Schmiedeberg's archives of pharmacology · 1997
- Nemonapride for the treatment of schizophrenia.The American journal of psychiatry · 1997
- High-performance liquid chromatographic determination of nemonapride and desmethylnemonapride in human plasma using an electrochemical detection.Journal of chromatography. B, Biomedical sciences and applications · 1998
via PubMed
Wikidata facts
- Mass
- 387.171354752
- Has use
- medication
Show 5 more facts
- canonical SMILES
- O=C(NC1CCN(CC=2C=CC=CC2)C1C)C=3C=C(Cl)C(=CC3OC)NC
- isomeric SMILES
- C(N[C@H]1[C@@H](C)N(CC2=CC=CC=C2)CC1)(=O)C3=C(OC)C=C(NC)C(Cl)=C3
- subject has role
- dopamine antagonist
- chemical formula
- C₂₁H₂₆ClN₃O₂
- Commons category
- Nemonapride
Sources (2)
via Wikidata · CC0
Article · Español
Nemonaprida (エミレース, Emilace (JP)) es un antipsicótico atípico aprobado en Japón para el tratamiento de la esquizofrenia. Fue lanzado por Yamanouchi en 1991. La nemonaprida actúa como un antagonista de los receptores D2 y D3 y también es un potente agonista del Receptor 5-HT1A. Tiene afinidad por los receptores sigma.
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 8 languages
via Wikidata sitelinks · CC0