فينيليفرين

Key facts

Drug.KEGG2

D00511

Drug.ChEBI

8093

Drug.ChEMBL

1215

Drug.KEGG

D08365

Drug.Watchedfields

changed

Drug.verifiedrevid

464201108

Drug.image

Phenylephrine v2.svg

Drug.image_class

skin-invert-image

Drug.alt

Skeletal formula of phenylephrine

Drug.image2

(R)-Phenylephrine molecule ball.png

Drug.image_class2

bg-transparent

Drug.alt2

Ball-and-stick model of the phenylephrine molecule

Drug.tradename

Neosynephrine, Sudafed PE, others

Drug.licence_EU

yes

Drug.DailyMedID

Phenylephrine

Drug.routes_of_administration

By mouth, intranasal, ophthalmic, intravenous, intramuscular, rectal

Drug.class

α1-adrenergic receptor agonist; vasopressor

Drug.ATC_prefix

C01

via Wikipedia infobox

Chemical data

Formula

C9H13NO2

Molecular weight

167.2 g/mol

IUPAC name

3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol

SMILES

CNC[C@@H](C1=CC(=CC=C1)O)O

InChIKey

SONNWYBIRXJNDC-VIFPVBQESA-N

XLogP

-0.3

Polar surface area

52.5 Ų

H-bond donors

3

H-bond acceptors

3

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1952

Admin. routes

oral, parenteral, topical

Indications

cardiovascular disease, hypertension, neoplasm, stroke

via ChEMBL · EBI

• The safety of intracameral phenylephrine - A systematic review.Survey of ophthalmology · 2022
• Effects of phenylephrine on systemic and cerebral circulations in humans: a systematic review with mechanistic explanations.Anaesthesia · 2024
• Phenylephrine.Critical care nurse · 1989
• Effect of phenylephrine on cerebral oxygen saturation and cardiac output in adults when used to treat intraoperative hypotension: a systematic review.JBI evidence synthesis · 2021
• The haemodynamic effects of phenylephrine after cardiac surgery.Acta anaesthesiologica Scandinavica · 2023

via PubMed

Wikidata facts

Mass

167.094629

Has use

medication

via Wikidata · CC0