Structure via PubChem · Public domain (PubChem)
Fenilefrina
Sign in to saveAlso known as PEF100, m-oxedrine, metasynephrine, (-)-m-hydroxy-alpha-(methylaminomethyl)benzyl alcohol, (R)-3-[-1-hydroxy-2-(methylamino)ethyl]phenol, (R)-3-hydroxy-alpha-[(methylamino)methyl]-benzenemethanol, l-(3-hydroxyphenyl)-N-methylethanolamine, R(-)-phenylephrine
compuesto químico
Key facts
- Drug.KEGG2
- D00511
- Drug.ChEBI
- 8093
- Drug.ChEMBL
- 1215
- Drug.KEGG
- D08365
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464201108
- Drug.image
- Phenylephrine v2.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Skeletal formula of phenylephrine
- Drug.image2
- (R)-Phenylephrine molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Ball-and-stick model of the phenylephrine molecule
- Drug.tradename
- Neosynephrine, Sudafed PE, others
- Drug.licence_EU
- yes
- Drug.DailyMedID
- Phenylephrine
- Drug.routes_of_administration
- By mouth, intranasal, ophthalmic, intravenous, intramuscular, rectal
- Drug.class
- α1-adrenergic receptor agonist; vasopressor
- Drug.ATC_prefix
- C01
via Wikipedia infobox
Chemical data
- Formula
- C9H13NO2
- Molecular weight
- 167.2 g/mol
- IUPAC name
- 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
- SMILES
- CNC[C@@H](C1=CC(=CC=C1)O)O
- InChIKey
- SONNWYBIRXJNDC-VIFPVBQESA-N
- XLogP
- -0.3
- Polar surface area
- 52.5 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1952
- Admin. routes
- oral, parenteral, topical
- Indications
- cardiovascular disease, hypertension, neoplasm, stroke
via ChEMBL · EBI
Research
24,567 papers- The safety of intracameral phenylephrine - A systematic review.Survey of ophthalmology · 2022
- Effects of phenylephrine on systemic and cerebral circulations in humans: a systematic review with mechanistic explanations.Anaesthesia · 2024
- Phenylephrine.Critical care nurse · 1989
- Effect of phenylephrine on cerebral oxygen saturation and cardiac output in adults when used to treat intraoperative hypotension: a systematic review.JBI evidence synthesis · 2021
- The haemodynamic effects of phenylephrine after cardiac surgery.Acta anaesthesiologica Scandinavica · 2023
via PubMed
Wikidata facts
- Mass
- 167.094629
- Has use
- medication
Show 10 more facts
- chemical formula
- C₉H₁₃NO₂
- defined daily dose
- 4
- medical condition treated
- supraventricular tachycardia
- canonical SMILES
- CNCC(C1=CC(=CC=C1)O)O
- isomeric SMILES
- CNC[C@@H](C1=CC(=CC=C1)O)O
- World Health Organisation international non-proprietary name
- phenylephrine
- melting point
- 144
- Commons category
- Phenylephrine
- significant drug interaction
- phenelzine
- different from
- (+)-pseudoephedrine
via Wikidata · CC0
Article · Español
La fenilefrina, metaoxedrina o neooxedrina es un agonista α-1 selectivo (es decir estimula de manera selectiva los receptores α-1) usado principalmente como descongestivo y como un agente para dilatar la pupila e incrementar la presión arterial. La fenilefrina ha sido recientemente usado en el mercado como sustituto de la pseudoefedrina, aunque se ha sugerido que la fenilefrina tomada por vía oral no es más eficaz en sus acciones como descongestionante que un placebo.
Abstract from DBpedia / Wikipedia · CC BY-SA